Hepatoprotective and Antioxidant Effect ofBauhinia hookeriExtract against Carbon Tetrachloride-Induced Hepatotoxicity in Mice and Characterization of Its Bioactive Compounds by HPLC-PDA-ESI-MS/MS
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Hepatoprotective and Antioxidant Effect of Bauhinia hookeri Extract against Carbon Tetrachloride-Induced Hepatotoxicity in Mice and Characterization of Its Bioactive Compounds by HPLC-PDA-ESI-MS/MS
The hepatoprotective and antioxidant activity of Bauhinia hookeri ethanol extract (BHE) against CCl4-induced liver injury was investigated in mice. BHE was administered (500 and 1000 mg/kg/day) along with CCl4 for 6 weeks. The hepatic marker enzymes: alanine aminotransferase (ALT), aspartate aminotransferase (AST), and alkaline phosphatase (ALP) were determined in the serum. The antioxidant par...
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The present study was carried out to evaluate the hepatoprotective and antioxidant effect of the methanol extract of Eupatorium ayapana (MEEA) (Family- Asteraceae) leaves in Wistar albino rats. The different groups of animals were administered with carbon tetrachloride (CCl4) at 72 h interval. The MEEA at 100, 200 and 300 mg/kg and silymarin 25 mg/kg were administered to the CCl4 treated ...
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The present work examines the protective mechanisms of methanol extract of Oldenlandia umbellata (MEOU) in carbon tetrachloride intoxicated rats. Rats were treated with carbon tetrachloride at the dose of 1 ml/kg body weight intraperitonially once in every 72 hrs for 16 days. The hepatoprotective activity of methanol extract of Oldenlandia umbellata was evaluated by measuring levels of serum ma...
متن کاملhepatoprotective and antioxidant effects of eupatorium ayapana against carbon tetrachloride induced hepatotoxicity in rats
the present study was carried out to evaluate the hepatoprotective and antioxidant effect of the methanol extract of eupatorium ayapana (meea) (family- asteraceae) leaves in wistar albino rats. the different groups of animals were administered with carbon tetrachloride (ccl4) at 72 h interval. the meea at 100, 200 and 300 mg/kg and silymarin 25 mg/kg were administered to the ccl4 treated rats....
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ژورنال
عنوان ژورنال: BioMed Research International
سال: 2014
ISSN: 2314-6133,2314-6141
DOI: 10.1155/2014/245171